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Model organisms are commonly used to investigate the probable causes of all disease types and the most favorable treatments for each disorder. Because all living organisms and their consistent DNA models are descended from common developmental pathways and genetic material, studies and results using these non-human organisms can theoretically be transferred to the human genome to ultimately identify appropriate treatment. Find the Assay for Your Target Gene Applied Biosystems is committed to developing tools and solutions that accelerate obtaining high quality results from model organism research. In addition to the over 500,000 TaqMan® Gene Expression Assays, for human, mouse and rat models, Applied Biosystems also offers over 300,000 pre-designed assays for many other non-traditional model organisms to provide the most comprehensive set of pre-designed real-time PCR assays. Eliminate the Expense and Time of Primer Design and PCR Optimization All TaqMan Gene Expression Assays have been designed through our validated bioinformatics pipeline, and run with the same PCR conditions, eliminating the need to design primers or optimize PCR conditions.
Specific and Sensitive Solutions for Microarray Validation Microarrays are commonly used tool for genome-wide expression analysis and initial gene target discovery. However, variability in microarray results exists from lab to lab, user to user, and platform to platform requiring validation with an alternative platform. The breadth of our TaqMan Gene Expression Assays collection, coupled with their industry-leading sensitivity and specificity, offers the ideal means to verify gene targets and quantitatively validate that genes of interest are truly differentially expressed.
TaqMan Gene Expression Assays were used as the gold standard in the MicroArray Quality Control (MAQC) Project, which compared data from seven microarray platforms (Nature Biotechnology, September 2006). TaqMan® Assays have the highest specificity, highest sensitivity and the largest dynamic range of any gene expression technology.
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