|
 |
Microarrays are an excellent tool for initial target discovery. However, variability in microarray results exists from lab to lab, user to user, platform to platform, and every combination thereof. Additionally, the relatively limited dynamic range of fluorescent microarrays (102-103) places limits on the technology with respect to sensitivity and specificity. It is therefore essential to use independent means to verify that genes of interest are differentially expressed, and to what extent.
-
TaqMan® Gene Expression Assays were used as the Gold Standard in the MicroArray Quality Control (MAQC) Project, which compared data from seven microarray platforms (Nature Biotechnology, September 2006). TaqMan® Assays have the highest specificity, highest sensitivity and the largest dynamic range of any gene expression technology.
- Affordably priced, these pre-designed assays eliminate the cost and labor barriers historically associated with TaqMan® probe-based 5' nuclease chemistry. Researchers can receive targets of interest immediately, and the breadth of assays available makes accurate microarray validation possible. The UMapIt Microarray-to-TaqMan® Assays Mapping Tool quickly finds the appropriate TaqMan Assay to validate microarray results.
- TaqMan® Arrays are the perfect tool for validating the tens or hundreds of hits that come from microarrays. They include from 12-384 TaqMan® Gene Expression Assays in one easy-to-use micro fluidic card. TaqMan® Arrays enable researchers to accomplish the validation necessary to arrive at the right answer easily and affordably. Arrays can be customized with the TaqMan Assays of your choice.
To see how TaqMan® Gene Expression Assays and Arrays are the most accurate, precise, and cost-effective method for validating microarray results, download the TaqMan® Gene Expression Assays White Paper.
For Research Use Only. Not for use in diagnostic procedures.
|
|
|
|
